29 APRIL 2021
Scientists have discovered a psychedelic-like drug that can produce rapid, long-lasting antidepressant effects in mice without the effect of hallucinations.
The molecule, called AAZ-A-154, acts on the same serotonin receptors in the brain as antipsychotic drugs (like clozapine) and psychedelics (like LSD), promoting neuronal growth and producing beneficial behaviors in rodents for weeks after a single dose.
Researchers say the treatment is comparable to the fast-acting nature of ketamine, which has recently emerged as a promising drug for conditions like depression, substance abuse, and post-traumatic stress disorder.
However, some psychedelic drugs that are being investigated for their medical effects, such as psilocybin, routinely trigger hallucinations, which means they should only really be used as a treatment under the guidance and supervision of experts.
Novo Seeds co-leads Adcendo s EUR 51 Million Series A Financing to Advance Novel Antibody-Drug Conjugates for Treatment of Cancers
- Novo Seeds played instrumental role in supporting Adcendo from inception
- Plans to build a pipeline of ADCs directed at novel cancer targets
COPENHAGEN, Denmark, April 29, 2021 /PRNewswire/ Novo Seeds, the early stage investment and company creation team of Novo Holdings, announced today an investment in Adcendo, a Danish biotech company which is developing antibody-drug conjugates (ADCs) for the treatment of cancers. The EUR 51 million (US$ 62 million) Series A financing was led by Novo Seeds and Ysios Capital, along with RA Capital Management, HealthCap and Gilde Healthcare.
Woolworths bakery staffer asks customers to buy old bread first to prevent waste
Woolworths bakery staffer asks customers to buy old bread first. Video / TikTok
news.com.au
A Woolies bakery worker has issued a public plea for customers to stop buying bread with the furthest away expiry dates, claiming it causes unnecessary food waste.
Back in February TikTok user @tony.zakharia2 shared how the clips on loaves of bread will usually correspond to what day it was baked and was a guide to which one was the freshest.
His video went viral, with plenty of customers responding that they always went by the bag clip colour or picked the bread at the back so they could get the freshest loaf.
Apr 28, 2021
Chelsea Clinton s
KRISTEN BELL were very open with their kids about it.
Which wasn t too hard, because they ve always known about daddy s addiction issues. Maybe they know a little too much.
One time when their oldest daughter was three, Dax was getting ready to leave for an AA meeting. She asked him why he had to go, and he said, quote, Because I m an alcoholic and if I don t go there, then I ll drink and then I ll be a terrible dad.
She asked Dax if she could go too, and he said no, you have to be an alcoholic. So she said, quote, I m gonna be an alcoholic.
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BENGALURU (Reuters) - India s Syngene International Ltd aims to supply half-a-million vials of COVID-19 drug remdesivir through its local distribution partners next month, its top executive said, as the country faces shortages of the medicine amid a second wave. At the moment we are operating at near maximum capacity (to produce remdesivir), Chief Executive Officer Jonathan Hunt told Reuters on Wednesday. I d expect the volume of drug that we are supplying into the Indian market to step up as we get into May, he added.
Hunt did not provide details on how many vials the company has already delivered.